Abstract
In this project, four N-quaternary phosphoniun chitosan derivatives (NQPCS) were synthesized by chitosan and four (N-carboxyalkyl) triphenylphosphonium of compounds (CATPPs). The cytocompatibility were evaluated by L929 fibroblast proliferation and cytotoxicity. Our goal is to demonstrate NQPCS can be applied in textiles, cosmetic and biomedical fields.
Keywords摘要
本研究係以幾丁聚醣與分別與4種N-(羧烷基)三苯基溴化鏻化合物(CATPPs)反應而得4種鏻化幾丁聚醣衍生物(NQPCS)。細胞相容性以L929纖維母細胞來評估其細胞成長活性與細胞毒性。期證明本研究所合成之NQPCS能應用於紡織領域、化妝品及生物醫學等用途。
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