Abstract
In this experiment, a composite nanofiber membrane was prepared by electrospinning technology and applied to a wound dressing fiber membrane. The hydrophobicity of the chemical structure of polycaprolactone (PCL) is improved by adding acrylic acid (Acrylic acid, AA) monomer to improve the hydrophobic properties of PCL. This experiment explores the addition of different proportions of AA monomer and also adds Ethylene glycol dimethylacrylate (EGDMA) and 2-Hydroxy-2-methylpropiophenone were used to prepare different ratio of PCL/PAA by electrospinning and photopolymerization. PCL/PAA composite nanofiber morphology and water absorption properties to achieve increased cell attachment properties
Keywords摘要
聚己?酯(Polycaprolactone, PCL)其化學結構的疏水性,透過添加丙烯酸(Acrylic acid,AA)單體,由於AA具有較佳的吸水性,改善PCL疏水性,以達到增加細胞貼附的性質。本實驗透過添加不同比例之AA單體於PCL電紡溶液,並加入交鏈劑乙二醇二甲基丙烯酸酯(Ethylene glycol dimethylacrylate, EGDMA)與光起始劑(2-Hydroxy-2-methylpropiophenone),探討PCL/AA溶液之導電及黏度的性質,並藉由靜電紡絲與光聚合方式製備不同比例PCL/PAA複合奈米纖維膜,且PAA具有抗菌效果,應用於傷口敷料纖維膜。
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